The CLEC4M antibody from Wuhan Fine Biotech Co., Ltd. is a Rabbit Polyclonal antibody to CLEC4M. This antibody recognizes Homo Sapiens, and Human antigen. The CLEC4M antibody has been validated for the following applications: EIA, Immunoassay, ELISA, Immunohistochemistry, and Western Blot.
Description
Probable pathogen-recognition receptor involved in peripheral immune surveillance in liver. May mediate the endocytosis of pathogens which are subsequently degraded in lysosomal compartments. Is a receptor for ICAM3, probably by binding to mannose-like carbohydrates. (Microbial infection) Acts as an attachment receptor for ebola virus(PubMed:12050398, PubMed:12502850). Acts as an attachment receptor for hepatitis C virus(PubMed:15371595, PubMed:16816373). Acts as an attachment receptor for HIV-1(PubMed:21277928, PubMed:12502850). Acts as an attachment receptor for human coronavirus 229E(PubMed:17037540). Acts as an attachment receptor for human cytomegalovirus/HHV-5(PubMed:12433371). Acts as an attachment receptor for influenzavirus(PubMed:21191006). Acts as an attachment receptor for SARS coronavirus(PubMed:15479853). Acts as an attachment receptor for west-nile virus(PubMed:16415006). Acts as an attachment receptor for Japanese encephalitis virus(PubMed:24623090). Acts as an attachment receptor for Marburg virus glycoprotein(PubMed:15479853). Recognition of M.bovis by dendritic cells may occur partially via this molecule(PubMed:21203928)